Looking At The Carer Prospects Of Foster Care Social Work Essay Essay Example

Looking At The Carer Prospects Of Foster Care Social Work Essay Essay This undertaking is based on a Foster attention appraisal of a prospective carer undertaken as a pupil societal worker. It gives an overview of my appraisal from allotment to cloture due to concerns. Although instantly allocated another more fruitful appraisal, I have chosen to look at this unsuccessful appraisal as I believe it taught me more as a pupil about my pattern. An bureau description is foremost provided to give the reader a image of the squad which should set my function into context. This is followed by the background and aims of my work. The chief text follows the natural patterned advance of my work from be aftering to rating. I will analyze my work placing the societal work subjects, issues and theories that guided my pattern. Reflection acknowledges that we are portion of what we are sing ( Schon, 1983 ) ; looking at our relationships with service users beneath the surface ( Payne, 2002 ) . I will therefore reflect throughout this undertaking, instead than strictly at the terminal, as this is what I of course did in my pattern. This will take to a brooding rating of my pattern and the deductions it had for both me and the service user. We will write a custom essay sample on Looking At The Carer Prospects Of Foster Care Social Work Essay specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Looking At The Carer Prospects Of Foster Care Social Work Essay specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Looking At The Carer Prospects Of Foster Care Social Work Essay specifically for you FOR ONLY $16.38 $13.9/page Hire Writer The bureau I was placed with was a statutory Foster attention squad within the local authorization s kids s services. Although the squad works more straight with surrogate carers it serves kids in demand between the ages of 0 and 16 and is hence classified as a Tier 4 service as shown below. Fostering services in this local authorization were originally integrated amongst other service user groups, regulated by the Boarding-Out Regulations ( 1955 ) . These ordinances caused ambiguity by promoting surrogate carers to handle surrogate kids as their ain ( Triseliotis et al. , 1995 ) . In the 1970 s, with the altering accent to the professionalization of fosterage, the squad bit by bit became a separate division. The 1955 ordinances were finally updated with the Boarding-out of Children ( Foster Placement ) Regulations ( 1988 ) which were later absorbed into the Children Act ( 1989 ) ordinances. Merely a few old ages subsequently the Foster Placement ( Children ) Regulations ( 1991 ) were introduced which changed the focal point of appraisal from families to single Foster parents. However, what both ordinances were missing was met in the constitution of the Fostering Services Regulations ( FCR ) ( 2002 ) and National Minimum Standards ( NMS ) ( Department of Health ( DoH ) , 2002 ) . These come under subdivisions 22 and 48 and 23 and 49 of the Care Standards Act ( 2000 ) severally. This changed the ordinance of the bureau from the local authorization itself to the National Care Standards Commission ( NCSC ) . The NCSC inspects how the bureau recruits, buttockss, supervises and trains surrogate carers. These four countries describe my function as a oversing societal worker within the squad. Background to the Case Monica is a 55 twelvemonth old female who had contacted the fosterage bureau with an involvement in going a surrogate carer. The procedure from public involvement to approved surrogate carer is complex and thorough. Each local Foster attention service will hold a similar but somewhat different process and the squad I was placed with used the procedure shown in figure 1. Initial Interest Initial Home Visit Application signifier sent and completed by Applicant Full Assessment by Social Worker taking to Fostering Panel Approved Foster Carer is allocated a Social Worker and begins furthering Figure 1: The Fostering Assessment Process When seeking to visualize the appraisal procedure for the reader, I felt a pyramid was the most appropriate. This is foremost because the broadness represents the greater personal investing a prospective carer must set into the fosterage procedure and secondly the deeper into their life a societal worker will and must travel. At each phase a prospective campaigner may hold a different societal worker. The initial place visit with Monica was conducted by another societal worker. The intent of this visit was to acquire a snap shooting of Monica s suitableness and motive to further. The societal workers study is so presented to senior staff with recommendations and a determination is made as to whether an application signifier should be sent. Once returned, the following measure is to travel through a procedure that combines elements of appraisal and readying ( McColgan, 1991 ) . This is where my engagement with Monica began. Aims of the Work As good as strong fond regards to household members, surrogate carers or residential attention workers are truly of import for kids in attention, as these are the people who have the most impact on their daily experiences ( DCSF, 2008, p.11 ) Foster carers are cardinal to many kids and immature people s experience of attention. It is indispensable that we value and back up them and guarantee that they are decently equipped with the necessary scope of accomplishments ( DfES, 2007, p.8-9 ) When measuring Monica I held the two statements above steadfastly in my head to utilize in times of uncertainness but besides clarity. It is good known that the enlisting and keeping of Foster carers has been systematically debatable for local governments ( Association of Directors of Social Services, 1997 ; Bebbington and Miles, 1990 ; Colton et al. 2008 ; Hill, 2000 ; NFCA, 1997 ) . Despite this, Quality Protects ( DoH, 1998 ) and the authorities s launch of Choice Protects in 2002 ( see everychildmatters.gov.uk ) continually try to raise the quality of furthering proviso to better arrangement pick and stableness. The green paper Every Child Matters ( DfES, 2003 ) and more late Care Matters ( DfES, 2007 ) argue that Foster attention services need carers with the accomplishments to look after vulnerable kids. In some states, such as Australia, the choice of Foster carers still has no empirical base beyond condemnable record cheques and suited adjustment ( Kennedy and Thorpe, 2006 ) . This was the past image in the UK, nevertheless the National Foster Care Association ( NFCA ) , now called The Fostering Network ( TFN ) introduced the Codes of Practice ( NFCA, 1999a ) and National Minimum Standards ( NFCA, 1999b ) for measuring surrogate carers. My appraisal of Monica would see her accomplishments, experience, values, cognition and overall suitableness to further kids for the local authorization. This was based on measuring her on four competences ( caring for kids ; supplying a safe and caring environment ; working as portion of a squad and ain development ) broken into 18 units ( Appendix A ) . More late the Children s Workforce Development Council ( CWDC ) has developed 7 criterions for surrogate carers ( 2007 ) ( Appendix B ) . The squad had merely begun utilizing these alongside the competences ( NFCA, 1999a, 1999b ) when I started Monica s appraisal. The criterions support a three phase preparation model for Foster attention ( pre-approval ; initiation and surrogate carer development ) . Pre-approval was my nonsubjective with Monica linked to subdivision 27 ( 1 ) of the FCR ( 2002 ) ( Appendix C ) , and other relevant statute law ( Appendix D ) . Although the FCR ( 2002 ) are the legislative force, it was the NMS ( DoH, 2002 ) under subdivision 17 which gave me a more elaborate apprehension of the countries ( caring ability, sexual boundaries, faith etc ) necessitating measuring with Monica ( Appendix E ) . Brown ( 1992 ) observes that a fosterage appraisal has two interrelated facets: ( a ) Evaluation of prospective carer s strengths and failings and ( B ) the appraisal of their capacity to larn, adapt and alteration. These aims are still relevant to measuring surrogate carers today. Whilst I was measuring Monica on the competences and CWDC criterions, there is no standardized manner of obtaining the grounds for these. I therefore felt I had a batch of discretion in my appraisal. I decided multiple cognition beginnings ( research, intuition and experience etc ) would steer my appraisal. Webb ( 2001 ) argues that Evidence Based Practice ( EBP ) can non work in societal work as the farewell of facts and values inherent in EBP undermines professional opinion and discretion. I disagreed and felt the usage of both grounds and my ain intuition was needed to obtain an accurate appraisal of Monica. For illustration, research states a demand for carers committed to developing after blessing ( H utchinson et al. , 2003 ) . However, I knew that merely because a carer agreed to developing after blessing that my intuition or pattern wisdom ( Stepney, 2000 ) may state me otherwise. Further, Sinclair s ( 2005 ) research underscoring the demand for betterments in surrogate carer choice, I felt, justified my usage of multiple cognition beginnings to make my aims with Monica. Planing for the Work When foremost allocated the appraisal of Monica, I was in the first hebdomad of my arrangement and true had small apprehension of what really made a good Foster carer beyond my ain common sense. This deficiency of cognition and apprehension left me experiencing out of my deepness and dying. I hence decided that before doing any contact with Monica I would garner all available information and utilize my bing cognition base to see how it fitted with the fostering appraisal. Brown ( 1992 ) suggests that when nearing a fostering appraisal we should inquire ourselves a scope of inquiries. The three I found myself inquiring were: what knowledge do I need ; is the assessment discriminatory or oppressive and what accomplishments and values do I need. Knowledge Gathering Appraisal is at the Centre of all good societal work pattern ( Bartlett, 1970 ; Milner and OByrne, 2002 ) and therefore my planning was important as failing to program is be aftering to neglect ( Trevithick, 2005, pg.140 ) . I wanted to utilize Monica s initial place visit study as my get downing point, as appraisals are seldom, if of all time, value free ( Rees, 1991 ) . Therefore before I understood any more about the fosterage procedure I wanted to place and look into any prejudice I may hold that could impact the appraisal undertaken ( Clifford, 1998 ) . However I was surprised by the studies deficiency of item and hence spoke to the societal worker who completed it. He could nt give me any extra information which frustrated me as the study, in my sentiment, failed to give the intended snapshot of Monica. This did nt assist alleviate my anxiousness, nevertheless reading the counsel Assessing surrogate carers: A societal workers guide to competency appraisals ( NFCA, 2000 ) increased my assurance of what I was expected to accomplish in my appraisal with Monica. Using this counsel coupled with the NMS ( DoH, 2002 ) and colleague information placed the appraisal of Monica in my head as undertaking centred pattern ( Doel, 1994, 2002 ; Reid and Epstein, 1972 ) . This was because the undertakings involved were non merely activities but held significance because of what they represented overall ( Coulshead and Orme, 2006 ) ; the fosterage of vulnerable kids. As fostering appraisals vary in length, typically between 4 months and a twelvemonth, I saw the appraisal as a uninterrupted procedure ( Hepworth et al. , 1997 ) . Therefore although my assessment visits would be based around specific undertakings and information assemblage, my appraisal of Monica would follow the ASPIRE theoretical acc ount ( Sutton, 1999 ) . This was because during my appraisal I would continually be after, step in, reappraisal and measure the appraisal with Monica. Oppression and Control From all available information beginnings, one issue rose within me. This was how intrusive the fostering appraisal appeared, and how for me, it epitomised the attention vs. control duality. Triseliotis et al. , ( 1995 ) believe that nowhere else are such inquiries asked with greater doggedness than in the appraisal of prospective Foster carers. They acknowledge that ways are being sought to do the procedure less intrusive and fairer to appliers. Although I saw the competences and criterions as one manner of accomplishing this with Monica, I still felt that I had a batch of power in her appraisal. Davis et al. , ( 1984 ) believe that the unequal power relationship between societal workers and appliers may advance the development of a relationship of dependance instead than the type of unfastened partnership required in furthering today. I viewed this unfastened partnership as being based on Monica s ego finding which to be met began with Monica voluntarily accepting my intercession ( Spicker, 1990 ) . My original thought was that subjugation merely applied to vulnerable groups. However, I knew I should avoid complacence as subjugation could go on to anybody, including Monica. In fact Monica had begun a Skills to Foster readying group and I had asked the facilitator of the group for some feedback. She described Monica as an interesting one noticing that she looked like she was approximately to drop dead. I discovered this judgement was based strictly on her usage of a walking assistance. Understating the impact of labelling ( Becker, 1963 ; Lemert, 1972 ) , I did nt desire this judgement to impact on me as I wanted to travel into Monica s appraisal with an anti-oppressive, non judgmental and accepting attitude ( Biestek, 1961 ) . Reflecting on my accomplishments and values Cardinal to our cognition base is the demand to cognize ourselves ( Dominelli, 2002 ; Crisp et al. , 2003 ) . Effective appraisal depends on the deployment of cardinal accomplishments such as Engagement ( Egan, 2002 ) , communicating, dialogue, determination devising ( Watson and West, 2006 ) and administrative accomplishments ( Coulshead and Orme, 2006 ) . I felt I already possessed the accomplishments needed and found it was my values in relation to this appraisal that were more hard to nail. As already stated, I did nt desire to label Monica but I did see her as an expert by experience instead than a service user , which is descriptive non of her as a individual but of our relationship ( McLaughlin, 2009 ) . Although engagement in societal work is determined by context ( Kirby et al. , 2003 ; Warren, 2007 ) I saw our relationship as mutual. I found the exchange theoretical account ( Smale et al. , 2000 ; Fook, 2002 ) of appraisal was peculiarly relevant in measuring Monica s ability to further kids, as she would evidently be more of an expert on her abilities. This really made me experience rather dying and powerless. This was, on contemplation, because as a adult male with no kids, I questioned my ability to measure an experient ex-childminding female parent. I took this to supervising and through treatment I understood that my virtuousness moralss ( McBeath and Webb, 2002 ) based on judgement, experience, apprehension, contemplation and temperament ; coupled with rem aining client centred and esteeming Monica as an person ( Dominelli, 2002 ; Middleton, 1997 ) would steer my appraisal. I saw myself as a hermeneutic worker moving in a brooding interpretive procedure between myself and Monica ( Gadamer, 1981 ) . Direct Work I had telephoned Monica and arranged to run into at her place. As the bulk of my visits would be two manner conversations between me and Monica I saw them as interviews with a specific and predetermined intent ( Barker, 2003, p. 227 ) . Eyess of a kid When set abouting Monica s appraisal, I tried to see everything non merely from the eyes of a professional but besides that of a kid. I understood that kids in the attention system would hold diverse demands and backgrounds ( Schofield et al. , 2000 ) with perchance a complex history of moves ( Ward et al. , 2006 ) . However I besides knew that attention can be a turning point and chance to raise kids, enabling them to carry through their possible ( Rutter, 1999 ; Schofield, 2001 ; Schofield and Beek, 2005 ) . Young people have commented that it is a surrogate carer s personality that makes the difference ( DfES, 2007b ) . Therefore by believing like a kid, I wanted to experience confident that by urging Monica to the fostering panel I could see she would be of great comfort and benefit to vulnerable immature people. Upon reaching at Monica s I was greeted by two aggressive Canis familiariss leaping and barking at the door. A tall compact adult male, who I later learnt was her boy, appeared from the garage and asked what I wanted. When inquiring for Monica he replied who wants to cognize . This ill will was shortly eased when I explained who I was, upon which he opened the door, called for Monica, and left me with both Canis familiariss leaping up at me. I felt that a kid come ining Monica s place was likely to be sing a scope of emotions, including anxiousness and from the eyes of a kid this would be chilling. Despite non the best of starts, I was determined non to do a judgement at a superficial degree ( Lloyd and Taylor, 1995 ) and to maintain an unfastened head about Monica s appraisal. Constructing a resonance Aware of the attention and control duality I wanted Monica to experience relaxed with me. I hence invested clip in acquiring to cognize approximately her as a individual before explicating the appraisal procedure. Although echt resonance can be questionable ( Feltham and Dryden, 1993 ) I felt my involvement in Monica was non-tokenistic, as I admired and respected her for desiring the ambitious function of furthering ( Kant, 1964 ) . I believe this was transmitted to her an enabled her to swear me. Monica talked about her household including the separation from her hubby. She besides spoke about caring for her ill female parent that caused her serious back jobs. Monica explained that she had a trim room and could nt believe of any better usage so for kids in demand of a loving place. Interestingly she went on to add well they might non desire to come here, I m a huffy lady and they might inquire: how would I suit into her universe . I found this look strange but following a gut feeling decided non to research at this point. I did this foremost because I did nt desire to look autocratic but secondly I felt my appraisal would subsequently supply beginnings of information that my intuition would be tested against ( Munro, 1996 ) . I explained the fostering appraisal procedure to Monica including the competences ( NFCA, 1999a ) and criterions ( CWDC, 2007 ) . I used a mixture of interpretive, descriptive and ground giving accounts ( Brown and Atkins, 1997 ) to guarantee Monica was clear of our hereafter work together. I commented you might be believing how a immature adult male without kids of his ain can can measure me in looking after kids . This elicited laugher from both Monica and me. As Kadushin and Kadushin ( 1997 ) explain laughter is an equaliser. It deflates ostentation. Workers capacity to express joy at themselves without embarrassment or shame communicates genuineness in the relationship ( pg. 225 ) . I besides believe it served a societal intent ( Foot, 1997 ) to switch power to Monica and do my following statement easier to present. I explained that in the fosterage appraisal it was expected that prospective campaigners were as unfastened and honest about their past experiences. I explained ab out confidentiality and that whilst non everything would be included in the fostering panel study, I could nt vouch absolute confidentiality ( Evans and Harris, 2004 ; Millstein, 2000 ; Swain, 2006 ) . I explained I would ever inform her if I needed to unwrap information and that personal information with no relevancy to her fostering ability would stay confidential. I believe this account built the needed trust ( Collingridge et al. , 2001 ) necessity for our relationship to advancement ( Leever et al. , 2002 ) . General Task Due to being my first visit, no specific undertakings had been set to discourse. Therefore reflexively I thought about the group facilitators earlier remarks about Monica dropping dead as I had noticed her walking assistance. I wanted to reflexivity dispute how I made sense of Monica s fittingness ( White, 2001 ) by making more cognition about this ( DCruz et al. , 2007 ) and maintaining the power balanced towards her. We hence completed a needed medical questionnaire. Monica stated, this is the spot I was worried about . Homing in on this anxiousness and apprehension that she may experience criticised ( Lishman, 1994 ) , I used reassurance to expose regard ( Clark, 2000 ) . I explained that I was non seeking to categorize her as either eligible or ineligible ( Fook, 2002 ) but a medical was expected of all carers. Monica explained that she was diabetic and was commanding this without her medicine and GP s cognition. I explored this with Monica and the possible impact for a vulnera ble kid, saying I would necessitate to discourse with my supervisor. Whilst traveling through the medical questionnaire Monica did nt advert her mobility job and therefore I probed about this. This achieved its coveted consequence ( Egan, 2002 ) as I learnt that Monica was registered handicapped and had nt been able to work for two old ages. Monica exclaimed that s it now is nt it . I truly valued Monica and thanked her for being honest with me. I stated that I was really more concerned about the diabetes so her disablement. My ain values were that every bit long as a kid was safe, so any individual regardless of disablement should be able to further. I set Monica the undertaking of building her chronology to discourse in our following visit and left her place. Supervision Supervision is non merely to help practician s development ( Hawkins and Shohet, 2000 ) but besides the demands of service users ( Pritchard, 1995 ) . I raised my concerns environing Monica s diabetes. I besides raised concerns environing the general province of Monica s place which was highly run down, covered in Canis familiaris hairs and had peculiarly hapless air quality. Using the hierarchy of attentivenesss ( Maslow, 1954 ) I saw how of import the house would be in run intoing the kid s basic demands and therefore its possible impact on a kid making self realization. Hazard has assumed increasing importance in societal workers day-to-day activities ( Webb, 2006 ) and I found my supervisor and senior practician urging we close the appraisal based on hazard. However I viewed the state of affairs from a preventive hazard position ( Corby, 1996 ) and felt that with work and support Monica could still further. I put my instance to the squad director from a Disability Discrimination Act ( 1995 ) and Equality Act ( 2006 ) position, saying that there is a dominant political orientation of disablement where services tended to concentrate on incapacity ( Prime Minister s Strategy Unit, 2005 ; Thompson, 2001 ) . However I saw possible in Monica due to raising her boy independently and her childminding experience. I was granted to go on with my appraisal if Monica could turn to her wellness and family issues. Dalrymple and Burke ( 2006 ) believe that critical argument about personal, professional and organisational values is indispensable in covering with ethical quandary. Although co-workers will hold different point of views ( Watson, 2006 ) , I felt my co-workers were moving habitually seeing Monica s appraisal as impracticable. However I saw my function as besides moral worker ( Hyden, 1996 ) and felt, with the attention vs. control and anti-oppressive pattern in my head, that Monica deserve d the chance to do the necessary sensible accommodations. Discussion around issues On the 2nd visit I discussed the issues environing Monica s diabetes and she agreed to see the GP and get down to command this once more. Her recognition that she was just being obstinate and thought she knew best I believe showed that my actions were with her best involvements in head. I besides raised the topic of the cleanliness of her place. Monica did nt experience at that place was an issue as she and her boy had lived at that place with no concerns. At first I questioned my values and whether I was enforcing them upon her. I reflexively began believing about the Human Rights Act ( 1998 ) Article 8 Right to Respect for Family and Private Life . However I besides thought about how I felt when I had left after the first visit and once more took my point of view from a kid who would potentially be less healthy than me. Under Article 27 of the UN Convention on the Rights of the Child ( 1990 ) children have the right to a criterion of populating adequate to their physical, mental, religious, moral and societal development . I explained to Monica that I was non seeking to enforce my values and believes upon how she lived and utilizing motivational interviewing ( Miller and Rollnick, 2002 ) asked her to compare her house with her friends places. I had used this method in my first arrangement and believed its usage in placing disagreements was movable. My usage of this method obtained its acquired affect as Monica stated that she knew her house could be a batch cleaner but because of her disablement she could nt keep it. Researching this with job resolution ( Howe, 2007 ) identified the demand of her boy to assist keep the place, but Monica stated she did nt desire to trouble him. I was holding trouble understanding how Monica s boy fitted with her fosterage. From a systems theory position ( Goldstein, 1973 ; Specht and Vickery, 1977 ) I saw this as of import to Monica s appraisal as he was her chief support and therefore his behavior would impact upon both her and kids placed with her. When believing abou t the appraisal of surrogate carers we should be turn toing whether or non the household system is closed or open ( Shaw, 1989 ) . An unfastened household system is one that is accepting of alteration and more likely to offer successful arrangements. Monica explained her boy was apathetic but supportive of her fosterage. I explained that I would necessitate to interview him individually to turn to this issue at a ulterior point in the appraisal. Chronology I had asked Monica to finish her chronology which provides a history of important events in her life ( Parker and Bradely, 2007 ) . This was to measure one of the competences looking at how our ain experiences can impact us ( NFCA, 1999a ) . Monica discussed her life events but nil from her childhood. I asked her about her childhood and she said it was nt of import. I used disputing to help farther ego contemplation and apprehension ( Millar et al. , 1992 ) . Monica asked me about my remarks in our first meeting about being unfastened and honest and whether I needed to cognize everything. I stated I merely needed to cognize things that would impact on her ability to further. Monica began shouting and started to explicate to me that she had been sexually abused in childhood by her uncle. The information elicited took me by complete surprise and made me dying. I sat and listened to understand, sympathize and measure what Monica had disclosed ( Smith, 1997 ) . Reding techniques can be used across many societal work state of affairss ( Seden, 2005 ) and I felt I demonstrated the core/basic guidance accomplishments ( Rogers, 1951 ; 1961 ) required of societal workers ( Thompson, 2002 ) . However with something so entrenched and deep I felt I was nt in the place to research this. Monica stated she wanted to go on and I hence asked Monica her it s impact on her current life. She stated she still had the occasional black twenty-four hours where she could nt acquire out of bed. Care Matters ( DfES, 2007 ) states that we need carers who can stand in the kid s places ( p.46 ) to assist them modulate their feelings. Monica positively identified that she could symp athize with a sexually abused kid but so worryingly said that by speaking to a kid about their issues would assist barricade out her ain cheerless feelings. Anxiety can enrich the individuality of societal work pattern ( Miehls and Moffatt, 2000 ) . On speedy contemplation this anxiousness I felt enhanced the apprehension between me and Monica ( Ruch, 2002 ) and empowered her to state me that she still had her ain issues to turn to. Monica acknowledged that she had nt thought about the maltreatment for 40 old ages believing her disablement caused her depression. I talked with Monica whilst waiting for her friend to get to guarantee she was safe before I left and stated I would shortly be in touch. Endings After the visit I compiled my notes utilizing a funnel attack to polish my information ( Parker and Penhale, 1998 ) into a study for senior staff. I used theory to offer answerability to all involved, including Monica, in my determination to shut her appraisal ( Payne, 2005 ) . This was based on standard 6.1 of the NMS ( DoH, 2002 ) in doing available carers who provide a safe, healthy and nurturing environment ( p.11 ) . My co-workers supported my determination and said to direct Monica a shutting missive which I found insensitive and unacceptable. I wanted a more moral face to confront closing with Monica instead than a procedural closing ( Lloyd, 2006 ) as Monica had disclosed something highly personal to me and I respected her for this. Endings are planned from the beginning ( Kadushin and Kadushin, 1997 ) . The natural stoping would hold been showing Monica s appraisal to the fostering panel. Alternatively our stoping was on different footings in which I provided Monica with a scope of local bureaus that could offer aid or reding to turn to her ain issues. Brooding Evaluation As stated at the beginning of this study, I decided to take this unsuccessful appraisal to analyze instead than my ulterior successful appraisal. This may look strange to the reader as the latter carers are now approved and furthering. However although I could compose in equal length about the more successful appraisal, it was Monica s that taught me more about societal work and about myself. I felt Monica s appraisal demonstrated the acquisition and deployment of my cognition, accomplishments and values over the past two old ages. The wide scope of literature presented in this study pulls on old and new resources, showing the demand to systematically update my cognition in an of all time altering profession. Without this cognition I would neer hold been able to work with Monica. I believe my appraisal, communicating and interpersonal accomplishments demonstrated my competency ( OHagan, 1996 ) . This ensured a natural, about unconscious, usage of the ASPIRE theoretical account ( Sutton, 1999 ) throughout and intend I could accommodate to the state of affairs and react eclectically to Monica s state of affairs due to its complexness ( Cheetham et al. , 1992 ) . Integrity ( BASW, 2002 ) has been the most important value throughout my preparation. I believe it incorporates all values such as Biestek s ( 1961 ) rules. My unity ensured that I fought for the continuance of Moni ca s appraisal at one point ; working anti-oppressively, non-discriminately and contending against societal unfairnesss ( BASW, 2002 ) . However despite my strengths, I appreciate that ego cognition is cardinal to going a brooding practician ( Dominelli, 2002 ) ; necessitating an openness and ability to be self critical ( Trevithick, 2005 ) . With Monica s appraisal I was reminded of how pattern is nt straightforward and can invariably alter ( Parker and Bradley, 2007 ) . I went into this appraisal experiencing that everything would be distinct because Monica had been seen by another societal worker and therefore she must hold been a certainty for furthering. However my complacence and trust on other workers opinions did nt fix me for the information I was subsequently to have. Uncertainty is an inevitable portion of human interaction and determination devising ( Roy at al. , 2002 ) and is something I need to appreciate more and continually turn to within myself. I feel another country that I could hold improved upon was concentrating more on Monica s strengths as she demonstrated an interior resource in reacting to t he day-to-day challenges in her life ( Kisthardt, 1992 ) . I feel that although my determination would non hold changed, in future pattern I need to maintain a steadfast clasp on service user strengths to appreciate that there is room in appraisal to concentrate on the cognitive accomplishments, get bying mechanisms, interpersonal accomplishments and societal supports that can be built on as strengths ( Pierson ( 2002 ) . Although the appraisal had nt gone every bit planned for Monica, I still believe it had some positive impact upon her. Monica s childhood had been traumatic and I viewed this afterwards utilizing the Johari window ( Luft and Ingram, 1955 ) in figure 2 below. At first I had wondered whether Monica s maltreatment was merely an facet of her concealed ego. However what struck me afterwards was that Monica stated I have nt thought about that in over 40 old ages . I had nt attached any significance upon this statement, likely due to the emotiveness of the state of affairs. However upon contemplation I feel that Monica s childhood maltreatment was portion of her unconscious ego that had been repressed as a defense mechanism mechanism ( Freud, 1949 ) . Known Self Things we know about Ourselves and others know about us Hidden Self Things we know about ourselves that others do non cognize Blind Self Thingss others know about us that we do non cognize Unconscious Self Thingss neither we nor others know about us Figure 2: Johari Window ( Adapted from Luft and Ingham, 1955 ) Initially I felt that it may hold been incorrect for me to hold elicited such a strong emotion from Monica. However about 2 months subsequently I received a missive from her thanking me for my support. She was having guidance and although she acknowledged she had a long manner to travel commented that she had seen an betterment in her mobility. I am glad I neer pushed at what Monica meant when she commented I m a huffy lady as I believe my non-judgmental attitude and credence ( Biestek, 1961 ) ensured Monica discovered for herself what she meant by this statement. My determination to shut Monica s appraisal highlighted to me, as was my concern in my planning, that subjugation and power are built-in facets of the day-to-day lives of professionals ( Hugman, 1991 ) . In Monica s instance, although I believe I was non-oppressive working with her, I still felt I processed a certain sum of power. OSullivan states that effective determinations achieve the determination shaper s end ( 2000, p.85 ) . My end was to measure Monica s overall suitableness to further kids for the local authorization. I highlighted to the reader earlier that I held two statements in my head to utilize throughout Monica s appraisal. Although non the make up ones minding factor in my determination, they helped me to see that although I valued Monica and the strengths she possessed, her ain issues needed turn toing before going the cardinal figure to many vulnerable kids. One article I have ever found influential is Howe s Modernity, Postmodernity and Social Work ( 1994 ) . Howe sees societal work as dwelling of the beautiful ( aesthetics ) the good ( moralss ) and the true ( scientific discipline ) ( p.518 ) . The beautiful is when we care which I believe my actions for Monica demonstrated. The true is where change requires us to convey a matter-of-fact and scientific mentality on issues. I believe I used accumulated factual, pattern and self knowledge to assist Monica s state of affairs. Finally the good is when control is employed if behavior has a possible impact upon the community s overall good being. Control was, and still is, something I am uncomfortable with and believe this will ever be the instance. However I see in my pattern with Monica that some component of it was required, otherwise my pattern would hold convened against the rights of so many vulnerable kids. Like many others, the ground I chose societal work was for the chance to do a difference ( Audit Commission, 2002 ) . Milner and OByrne ( 2002 ) believe there is no individual right manner to analyze human state of affairss but we need to happen the terminal merchandise of a narrative that is helpful to all concerned. With Monica s appraisal I believe I achieved this by doing the difference non merely to her but besides to kids who I will neer even meet. It is with this satisfaction that I believe my work incorporates the moralss ( BASW, 2002 ) and pattern criterions ( GSCC, 2002 ) required of me post making. 5708- 296= 5412

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Atypical Pneumonia essays Atypical pneumonia, also known as walking pneumonia, is a common cause of community-acquired pneumonia. Mycoplasm pneumomiae is the responsible organism which results in pneumonia in only 3% of cases; 20% of infections are asymptomatic, while 77% involve the upper respiratory tract. Although atypical pneumonia can occur at any time of the year, outbreaks tend to occur in the fall. The incubation period averages 3 weeks, in contrast to that of influenza and other viral pneumonias, which generally are a few days. Epidemics of mycoplasmal pneumonia tend to occur every 4-8 years in the general population and tend to be more frequent within closed populations, such as in military and prison populations. Mycoplasmal pneumonia is a disease of insidious onset. The patients history may include fever and chills, malaise, worsening dry cough, headache, scratchy sore throat, sore chest and tracheal tenderness and pleuritic chest pain, which is usually rare. Most cases of pneumonia due to M pneumoniae resolve after several weeks, although a dry cough can be present for as long as a month; some patients can have a protracted illness lasting as long as 6 weeks. The physical exam will reveal a nontoxic general appearance, erythematous tympanic membranes or bullous myringitis, mild pharyngeal erythema with minimal or no cervical adenopathy and no exudates. Usually there is a normal chest and lung exam with early infection but rhonchi, rales, and/or wheezes are heard via auscultation several days later. Generally lab studies are not needed but can be obtained. Complete blood counts tend to be within normal limits or slightly elevated. Sedimentation rate can be elevated with prolong infections. Chest radiographs should be obtained for definitive diagnosis, however at times there are no findings on x-ray and the clinician should treat presumptively. Macrolide antibiotics such as Erythromycin or Azithromycin are the drug treatment of choice due ...

Assistance at National Investment and Insurance Essay

Assistance at National Investment and Insurance - Essay Example As the discussion declares an evolution of the concept of motivation is briefly outlined along with the major theories to enhance the perspective regarding the present context as well as justify the identification of the lack of motivation as the fundamental problematic for the ITS of NII. Based on the theories of motivation, two features of the part-time employment policy – no dependence of pay on performance and the lack of information regarding intrinsic benefits of working part-time in terms of future full time employment possibility, are identified as the fundamental problems that create an environment that does not provide any incentives to perform better. The report suggests redesigning the employment scheme and making a part of the pay dependent upon performance, i.e., introducing financial rewards as incentives to perform better as the first step. Secondly, it is suggested to introduce the intrinsic reward of higher possibility of being offered full-time employment gi ven higher performance. The subject of the given case study entitled â€Å"Assistance at National Investment and insurance† is the sub-optimality of the service provided by the employees of the IT support (ITS) section identified to be Assistance Officers (AOs) and the resulting performance of the department in totality. The study reports that from a survey conducted on National Investment and insurance (NII) employees who utilized services of the IT support section regarding the performance of the AOs emerged to be less than satisfactory. Apart from delayed responses and resolutions, unfriendly or mechanical attitudes were reported though surprisingly, the considerable majority of the problems addressed were

Introduce the two companies and explain the difference between a b2b Essay

Introduce the two companies and explain the difference between a b2b company and a b2c company - Essay Example is a B2B company since it provides manufactures and supplies microprocessors necessary for computer manufacturing companies such as Dell, HP, Samsung, Sony etc. On the other hand Dell is a B2C company since the products manufactured by this company is sold directly to the consumers. B2B and B2C companies differ in terms of marketing mix, product ranges, marketing communication, pricing and distribution Product, Price, Place and Promotion are considered as the four major elements of marketing mix (Ritcher, 2012). Intel is one of the major semiconductor chip manufacturers in the world. It supplies many types of semiconductor chips including microprocessors to prominent computer manufacturers as well as electronic devices manufacturers. Therefore, the company is targeting only the major manufacturers of electronic devices such as Dell, Sony, HP, Lenovo etc. Unlike B2C companies, B2B companies or Intel is operating through channel partners in different market. For example, LG, Lenovo, Dell and Zenith are some of the channel partners of Intel in different markets (Mody, 2007). Intel has a variable pricing strategy across the world. Since the company enjoys monopoly in some markets, it has the ability to fix the prices of its products in such markets. As in the case of B2C companies, Intel also use various promotion strategies to get more market share. â€Å"In 2006 Intel launched a fi ve-year campaign known as the ‘World Ahead Program’. This initiative is geared toward an increase in digital literacy, research, and development†(Flores, 2008). Dell on the other hand has a wide range of products such as workstations, desktops, desktops, tablets, etc. The company is marketing its products directly to the consumers with the help of advertising and promotion strategies. Promotion plays a big part in Dell’s marketing mix even though it plays less significant role in Intel’s marketing mix. Variable pricing mechanisms were implemented by dell in different markets based

Segregation Essay Example | Topics and Well Written Essays - 1250 words

Segregation - Essay Example Despite variety of theoretical models suggested by US scholars to explain the ongoing discrimination in various fields of social life (Massey & Denton 1993; Borjas 1998), the key question still remains unanswered: why several decades of intensive legal and social efforts did so little in terms of eliminating such negative phenomenon as discrimination of minorities Although legal status of minorities is an essential factor in fighting discrimination and segregation, there are likely other equally important factors involved. Main Discussion The efforts to cope with the problem of minorities' segregation and discrimination undertaken during the last five decades largely failed. The seeming success of affirmative action when in 1970 - 1980's the number of students who belonged to racial or national minorities significantly increased, was achieved by reverse discrimination of the white majority: cases of Bakke and Webber (Ball, 2000) in 1970's made this fact evident to the public. Eventually, the surveys of public opinion demonstrated the controversy caused by lack of understanding of the affirmative policy in the nation. A recent survey performed by CNN in 1995 discovered that 80 percent of the respondents felt "affirmative action programs for minorities and women should be continued at some level" (RCPO, 1995). However, at the same time any possibility of reverse discrimination, which in fact had been the main feature of affirmative action programs since 1964, was opposed by 63 percent of participants (RCPO, 1995a). Affirmative action programs in education seem to cause more damage than positive effects. Laws passed to protect minorities from discrimination often led to reverse discrimination instead of... One of the most known accounts of the relationship between prejudice and negative stereotype was suggested by Milton Rokeach, who established a strong link between prejudice and the perception of intergroup differences.Therefore, affiliation with a certain group is an essential aspect of any individual's life. However, an individual affiliated with a certain group starts to distinguish between his/her group and people who belong to other groups which result in the development of two concepts: in-group and out-group. In-group is defined as "†¦ a group to which a person belongs and which forms a part of his or her social identity" while out-group is "any group to which a person does not belong". The major difference between the individual's perception of in-group and out-group members is the following: members of in-groups possess overwhelmingly good personal qualities, while out-group members are perceived with a certain share of negativism. This unique psychological mechanism is likely to be an important contributor to the ongoing discrimination and segregation in the US. This mechanism provides a valid explanation for the phenomenon of ‘voluntary segregation': segregation and racial isolation which results from voluntary choices of the minority representatives in housing, education, etc. The set of negative stereotypes which developed over the centuries when the white majority and the minorities lived on the same territory is an equally important factor in the ongoing discrimination.

Pros And Cons Of Canadian Water Exports Environmental Sciences Essay

Pros And Cons Of Canadian Water Exports Environmental Sciences Essay Question ¼Ã… ¡ Water in the future could become as important as oil as a major source of world conflict. Canada will not have to worry about this and in fact will be a major player in the control and management of water. This assumes that we have an adequate surplus of water and that we can use this as an export product. Examine these ideas from both pro and con sides and develop a conclusion about our future use of water. Water has been a vital resource for many lifeline purposes such as drinking and hygienic purposed like cleaning. Throughout the human history, water has been considered as a cheap resource and abused to comply with human needs. Despite the numerous amounts of sources of water are found, the increasing of global population depletes the non-renewable resources as natural gas, coal and oil. This essay will try to examine the ideas that whether Canada can use the adequate surplus water as an export product or not, base on the water resource in the environment, new technologies applied to the water treatment and the advantage disadvantages of using water resources as an export product. Water is one of the most common and vital resource in our society and harnessing water has been quite easy in most part of the world. Water covers nearly three-quarters of the earths surface and also there is water in the atmosphere and underground. Its mainly in ocean but also found as rivers, lakes, snow and glaciers. In fact, 99% of all the fresh water is found in glaciers, ice fields and underground. However, atmosphere water (snow, rain, fog) and glacier are strongly depending on the weather movement of the earth. On the other hand, there are numerous ways to obtain water from nature; some of them are already available such as perennial sources like oceans, river, lakes and steam. The most convenient way is groundwater resources such as aquifers that make up the water table [1]. Furthermore, water is also available from time to time in the form of influent water sources such as the precipitation of rainfall and snow. As Figure 1 show below, there are 2 types of aquifers, confine d and unconfined aquifer, where the confine aquifers are sandwiched between two porous layers of rocks. The unconfined aquifers are the water between porous and nonporous rocks with can be replenished by rainfall or snow over time. Precipitation of water is still a major resource that people depend on in many part s of the world where the water table is not sufficient enough to the massing population. the adept use of technology, farmers learned to mine ground water to overcome the lack of enough rain(Opie.J,1993). The necessity of water for human life has driven the discovery the abundant water table beneath the ground, and the use of aquifers for domestic purpose has been practical and popular. Another important resource in some area includes the availability of glaciers. This is apparent in Armenia and Azerbaijan where the glaciate and snow-covered mountain are the water towers of the region providing resources for irrigation, industrial, and domestic use which makes it an essent ial need to monitor and protect the ice caps from melting(Jones, 2009). Canada is fortunate, it has only 0.5% of the worlds population, but its land contains about 7% of the worlds renewable water supply. Also, the industry is the major consumer which occupies about 56.3 % of the water consumption, domestic is about 23.7% and agriculture is only 20%. Thousands of dams has erected in a river of stream to block the flow of water so that water can be stored and reservoir. The dams were built to prevent flooding, supply of drinking water, facilitate irrigation, and generate electricity. The placement of dams also have disadvantages such as habitat alteration, fisheries declining along the downstream of the dam, population displacement because of the water level inside the before the dam, sediment capture before the dam and so on. Through the recent research, people have overused the surface water to suit our needs. The water level of the dam and also the water level of the Ontario Lake had drop a significant height from 2009 to 2010. On the other hand, we ar e depleting groundwater which is more easily depleted than the surface water, because it is easier to use up the water resources but most aquifers recharge very slowly. Today people are extracting 160Km3 more water each year than is finding its way back to the ground, the major problem is the increasing of the human population and the area of the city are increasing also, which most of the surface water from the rainfall will run off and affects the amount of water could recharge into to aquifers. In some part of Mexico, India, China, and other Asian and Middle Eastern nations, water tables are falling 1-3 meters per year (book). Human activity has strongly affected the environment as shown in the history, which is also affecting the most important resource water and causing water pollution. It includes acid rain, erosion and sedimentation, groundwater contamination and waste water: Acid rain is that water vapor has been contaminated with chemicals introduced into the atmosphere by automobile and industrial emissions. The precipitation rain has a much higher acidity than clean rain water. The most common chemicals are nitrogen oxides and sulphur formed sulphuric acid and nitric acid. Erosion and sedimentation means water plays as a role in transporting the landscape by moving the large amount of soil, also is sediment. Sediment is eroding from the land, transport by the river or stream system, and finally deposited into the lakes or ocean. The sediment starts with erosion of the landscape, including particles or fragments from the rock material, carried by wind and rainfall, plant and animal activities also contribute to the erosion of the earth surface. Groundwater contamination is the addition of undesirable substance to ground water layer by human activities. It also has been assumed that any contaminates left on or buried under the ground caused groundwater contamination. For example, people dumping waste or toxic material into the wells; some countrys government buried the regularly garbage under certain area. Groundwater contamination is extremely difficult to clean up, sometimes is impossible. Waste water is the released of contaminated water from different industries. The government of Canada is taking the lead in proposing regulations, federal and other wastewater systems, which include standards for national wastewater effluent quality and provide regulatory clarity for rules on reporting for more than 3,700 Canadian facilities.(Environment Canada, 2009) some examples of pollutant that affects the ecosystems and human health include: decaying organic matter and debris can use up the dissolved oxygen in a lake so fish and other aquatic biota cannot survive; excessive nutrients such as phosphorus and nitrogen/ammonia can cause eutrophication, or over-fertilization of receiving water, which can be toxic to aquatic organism, promote excessive plant growth, reducing the oxygen in the water. Furthermore, the above pollution will recycle and mix by the water recycles flow chart. The pollutant/ contaminate is first released to the earth surface or air, carries by the wind and precipitation, rainfalls to the ground, because of the acid rain will erode the soil and rocks, more sediment is easier to be washed by the water, and contaminated the rivers and underground water, finally theses pollutant stays in the ocean or lakes which may pose threats to human health, aquatic life and wild life. Since the industry has consumed most of the water in Canada with most releasing water pollution such as air pollution and wastewater pollution. It is better to prevent the pollution than to migrate or clear the impact after it occurs. Although the nature system can process a certain amount of waste water, the huge and concentrated amount that generated by our industry can harm ecosystems and threat the human health. Therefore, wastewater treatment has to be done before releasing it to the environment. The first step is physical removal of the Suspended particles by filtration, follow by treatment name Primary Clarifier is to separate the organic substance including gas and liquid, then a secondary treatment, in which water is stirred and aerated so that aerobic bacteria degrade organic pollutant, finally filtering and disinfection is applied to the water tank, and effluent discharge into waterways. During the this process, some of the waste solid particle will be disposed at landfill, or burnt in with gas in a chemical burner. On the other hand, some solid are removed and sent to anaerobic digester, which will produce gas for electricity or biosolids for cropland. The water quantity and water quality in Canada is one of the best in the world, in the future, water will become as important as oil and it will be used as an export product. Obviously, the advantage is the revenue that water can create a huge economy benefit for our country. However, we have to face some practical problems. On the environmental side, the renewable fresh water is decreasing from the last decay all over the world, as the increasing of population, growing of social economy and climate change(due to global warming), the total fresh water resource in Canada is also decreasing. On the human activity side, more dams have been erected, more industries have built and more pollution has been released into the environment, which means more water management and wastewater treatment are needed to ensure there is no contamination of the fresh water resource, no harm to the ecosystem and the human health. On the technologies side, if water has been considered as an export product, how can we export water from our country to another which may be very long distance transportation? How can we ensure the quality of the water to customers? How can we secure our water resource from other consumer, since the water in the river, steam and underground is flowing all the time from one country to another? and finally how do we evaluate the cost verse the revenue of our water product. http://citationmachine.net/ http://www.scanmyessay.com/ http://geoscape.nrcan.gc.ca/h2o/bowen/underground_e.php http://www.ildtechnologies.com/water-waste.htm

The Benefits of Stem Cell Research Essay example -- Papers Science Bio

The Benefits of Stem Cell Research Stem cells are considered â€Å"master cells† with the ability to divide for indefinite periods in cultures and can be manipulated and transformed into any type of cell in the body. The most common use would be the generation of cells and tissues that could be used to either create organs or tissues to be used in transplantation and to treat many diseases and disabilities. There is a great difference of opinion surrounding stem cell research; conservatives and pro-choice activists are highly against further research, but the tremendous advances in health care and President Bush’s recent decision to fund more research, have made the future of stem cells seem much more promising. In every ground breaking scientific topic there seems to be controversy, and stem cells are no exception. Stem cell research is so controversial because the best source of stem cells are derived from human fetal tissue. Removing the stem cells destroys the embryo, which leads many people to believe this process to be immoral. One advantage of using stem cells found in embryos is their ability to transform themselves into almost every type of cell in the body. There are also not enough adult stem cells to allow for therapeutic applications, like transplants to regenerate tissues or organs that were damaged by disease. Adult stem cells are rare and are many times hard to identify, isolate, and purify. However, stem cells found in the embryo can be generated in large quantities in the laboratory. Many people argue that human embryos should not be the subjects of stem cell research that would benefit anyone other than the embryos themselves. Embryos are still human beings and just because they are immature hu... ...purpose of stem cell research. Generous funding on ethical issues was spent on current and future research, along with generous funding for research relevant to fetal, embryonic, and adult stem cells. With the enormous potential of stem cells developing new treatments for some of the most devastating diseases, it is crucial to search for the best sources of stem cells, regardless of where they come from. There are many pros and cons encompassing this issue with the pro-choice activists and conservatives being so avidly against it, with the remarkable advances in health care the research brings, and with President Bush’s decision to go ahead with further research. Even though there is still a great deal of controversy surrounding the issue of stem cell research, I think all people can agree that whoever saves one life is as if he saved an entire world.

Education On Health Promotion Essay

Q. 1 Validity is said to be the power to convince about the conclusions that have been found. It is the strength that the conclusion has to convince others on the facts that have been outlined. There are said to be four types of validity namely external, conclusion, construct and internal validity (http://www. brainyquote. com). The external validity is about the ability to generalize the findings to other settings, the conclusion looks for a relationship between the outcomes and the program, the construct validity determines the presence of a relationship between concepts in a study and an actual casual relationship and finally the internal validity looks for the relationship between the study object and the outcomes of the study. On the other hand, reliability is said to be the ability to get the same results over and over again when performing the same test at different times (http://www. asiamarketresearch. com). It is said to estimate how consistent your measurements are. For a tool of measurement to be reliable, it has to give the same results when used at different times by different people to measure the same thing. It can be tested through using different questions that measure the same thing to see if the answers are consistent while the test/retest method means getting the same findings for the same test done at different times but under the same conditions. Validity and reliability will be used in the dissertation to test the conclusion. First checking on the reliability of the tools of measurements does this. This ensures that the data provided for the study is to be trusted as being correct. It also helps eliminate the data that contains some inconsistencies. Once all the reliable data has been compiled, it can then be used to arrive at some conclusion. This conclusion will be valid if all the measurements that have been done have involved the data that was supposed to be measured. If one has been using the correct data using reliable tools then the conclusion will be a valid one. The correct questions have to be asked in relation to the topic and the measurement tools have to be reliable for the conclusion to be valid. Q. 2 When starting a project one begins with choosing a topic on which to research on (http://www. ri. net/schools/East_Greenwich/research. html). This topic should not be too general as to include subjects that are not relevant to the researcher instead it should be very specific on what is to be research on. When choosing a topic, one uses the tool of research called the â€Å"human mind†. This is because a topic is chosen according to how the researcher perceives the surroundings and thus requires reasoning and analyzing which uses the brain. Next is gathering the relevant background information concerning the topic. This can be done through the use of the computer and its software. It is done to get the most basic information on the chosen topic. This information can be supplemented by the use of the library where one can find encyclopedias among other sources. This information is used to refine the chosen topic (http://www. ri. net/schools/East_Greenwich/research. html). If there is need to change the research topic it is done now. After revisiting your topic, you now need to gather the information needed. This is done by the use of the computer and the library. This information is then supplemented by fieldwork, which uses different methods of gathering information. This is done to confirm or challenge the statistics gotten from the library and computer software. While conducting the field research, one has to estimate the reality of the tools of measurement so as to ensure the information gotten is correct and in the process eliminate those, which contain errors after this is done, the information is coded and analyzed. The information is now ready for use to get the conclusion and then organize it to be able to write it in a way that the reader will understand. When it comes to the writing part, the language to be used has to be chosen carefully. It has to be a language accessible to all the presumed readers. The research is then written and is used to justify the problem statement and why the project should be undertaken. The conducting of a research and writing of a dissertation are the actual start of a project. This is because they justify the reason why the project can now start. All the six tools of research are used to ensure that the information provided in the research is reliable and valid. One can only gain experience in the use of these tools by conducting many researches. By writing dissertations and research papers, one ahs to use these tools and in so doing gets a lot of experience in their use. Over time one gets to learn how to use the various tools. When it comes to computers, one has to solicit the help of computer experts an also using the help icon in the computer. For a researcher, it is very useful to join research projects as an assistant researcher. This ensures that one gains a lot of experience and by working with an expert researcher one is able to pick up quite a number of tricks in the research field. Also as a research assistant, one does a lot of work and so is able to come up with new and more effective ways of using the tools of research. On top of this, one is able to choose which tools they can use best and which ones they need to work on to understand how they are used. To learn to be an expert researcher, one can only go through the above mentioned process of first becoming a research assistant. The expert researcher has to be able to use the six tools of research namely the human mind, the computer and its software, the statistics, the traditional library, tools of measurement and the language facility. It one has gone through the process of becoming a research assistant, there is knowledge gained from constant use of the tools and one can then be able to decide which tools they are most comfortable using. All the tools are important and necessary to any researcher but the order of importance assigned to each tool is what differs from researcher to researcher. It is only through experience of having worked on many research projects does one become competent in the use of all the tools and so that is what any novice researcher concentrates more on. Q. 3 The dissertation topic is education on health promotion.  From the interview with the researcher, I have learned how to use the six tools of research in the dissertation topic. By using the human mind, the topic, which is education on health promotion, was chosen. Using the computer and its software, the topic will be researched on and the basic knowledge gathered. Since the topic has enough materials to be used, it will not be changed. The information is then supplemented with that from the traditional library. After the topic has been re-affirmed, the field information will be collected and this will be done by using tools of measurement that are reliable (http://www. ih. gov/news/researchtools/). Once the information has been collected, it is then analyzed, cleaned and coded. The findings will now be used in writing the paper. When writing the paper the language to be used has to be that which the targeted readers can understand. When writing one has to avoid plagiarism and ensuring that any information from other sources is cited will do this. The paper must be in the proper format and should include all the parts of a project paper. The conclusion will have to support the topic and reason for the research. It will therefore have to support education on health promotion

Central and Eastern Europe Environmental Issues Essay Example

Central and Eastern Europe Environmental Issues Essay Example Central and Eastern Europe Environmental Issues Paper Central and Eastern Europe Environmental Issues Paper Essay Topic: East Of Eden Abstract Eastern Rupees environmental problems are not as simple as they may seem on the surface. The environmental problems that face Eastern Europe are complicated by political, economic, and social implications. The current environmental problems are a bi-product of rapid industrial expansion under a socialist government. The soviet government was more concerned with surpassing the western cultures in technology and military might than the environmental damage they were doing to their country. The following paragraphs will address the current environmental problems facing Eastern Europe, the various solutions to the environmental problems, and the efforts taken to correct the environmental problems. Environmental Problems in Europe Eastern Europe during the asses had rapidly become the industrial giant for the Soviet Union. Massive industrial factories would be built throughout the eastern bloc of the Soviet Union and the factories used obsolete technology to provide the industrial needs of the country. The heavy industrial activity characteristic of the post-World War II period took a heavy toll on both the regions population and its environment(LLC. S. Environmental Protection Agency, 2010). Various local populations were suffering from high rates of cancer, respiratory issues, and infant moralities. The environments in the areas around the industrial regions were also being damaged on unprecedented levels. Legacy of Pollution According to the U. S. Environmental Protection Agency (2010), The outmoded, energy-intensive technologies were such an integral part of Central and Eastern Europe (ICE) and New Independent States of the former Soviet Union (ENS) regions economy in the post-war era not only wasted sources, but also caused severe local, regional, and trans-boundary pollution problems. Not only was the industrial technology outdated, the communication among the post-war government, local governments, and various environmental ministries was ripe with secrecy and non-communication between each other. The results would prove to be catastrophic pollution of the air, surface water, soil, ground water, marine zones, and coastal areas. Air Pollution Air pollution in Eastern Europe is the top concern because of the levels of sulfur dioxide found in all the industrial areas. High levels of sulfur dioxide exposure can lead to asthmatic children and adults, respiratory illness, decreased lung defenses, and worsening Of existing cardiovascular diseases. When Sulfur Dioxide is exposed to rain it creates acid rain and raises the acidity level of everything it touches such as soil, lakes, and streams. Buildings corrode faster and there is also a reduction in visibility. Water Pollution Agricultural and industrial practices were causing large spread water pollution because of outdated waste regulation practices and no environmental regulation. According to Oilier (1 990), Drinking-water supplies throughout Eastern Europe are heavily contaminated. Vast reaches of the Fistula River in Poland, which drains much of the country, are classified as unfit for use even by industry. The Baltic and Black Sea coasts are badly degraded by domestic sewage, agricultural run-off, and heavy metals and organic pollutants from industry. The Eastern Europe governments have been slow to implement solutions to purify the drinking water in the various regions. Soil Pollution Samples of produce from upper Poland have yielded 30 to 70 higher regenerates of cadmium, lead, zinc and mercury then acceptable levels listed by the World Health Organization. The high percentages of these heavy materials indicate how polluted the soil is in the upper polish regions. In Hungary alone, waste generators dispose Of more than 500,000 tons waste found in illegal landfills. The local government has trouble tracking any kind of waste transportation and disposal due to obsolete tracking processes, and because not all waste is indicated as waste before being disposed of. Eastern Europe is wreaked with not only environmental problems, but also tit government, and local government problems also. The good news is that there are viable solutions to the environmental problems that the Eastern Europe countries are having. Viable Environmental Solutions The environmental problems that face Central and Eastern Europe are much the same as any other country in the world with one exception, the proximity of the environmental hazards. Most countries in the world deal with environmental hazards, but the hazards are spread out over different parts of the country. Central and Eastern Europe are unique when it comes o environmental disasters because Central and Eastern Europe was the industrial might behind the soviet military. For every environmental disaster Central and Eastern Europe faces, there is a viable solution thanks to modern technology and proven environmental regulations. Possible environmental solutions Because of the vast environmental disasters throughout Central and Eastern Europe there are several possible environmental solutions. The possible environmental solutions that Central and Eastern Europe are considering will be decided by the cost of the solution, ease of implementation, and consultation from environmental agencies such as the United States Environmental Agency. Even with the various economic, governmental agency communication problems, and various ecological disasters Central and Eastern Europe have a number of viable solutions. Air Pollution Solutions One of the possible remedies for air quality in Europe would be to switch to burning low sulfur coal. When coal is burned, carbon dioxide, sulfur dioxide, nitrogen oxides, and mercury compounds are released. For that reason, coal- fired boilers are required to have control devices to reduce the amount of missions that are released. The amount of sulfur oxides produced by power can be reduced by using coal with low amounts of sulfur present. Another possible air solution would be to use scrubbers. Scrubbers are an air pollution control system that removes pollutants from the air stream they are most commonly used to help control the emissions of sulfur into our air. There are a few pipes of scrubber, Air scrubbers, wet scrubbers, and gas scrubbers are differentiated by the manner in which they remove gases and particulates from the air; either wet or dry. Wet scrubbers literally wash dust ND particles out of the air. Exhaust air is forced into a spray chamber, where fine water particles cause the dust to drop from the air stream. The dust- laden water is then treated to remove the solid material and is often re- circulated. Dry scrubbers are used more commonly with acid gases. The pollutant is collected On or in a solid or liquid material, which is injected into the gas stream. A dry scrubber produces a dry product that must be collected downstream from this control device. Water Pollution Solutions One of the many possible water pollution solutions would be aeration. Aerating is the process to bring river water at the bottom of rivers up to the surface so that the entire river is oxygenated by the atmosphere surface to bottom. They can do this by pumping air into bodies of water at the very bottom. On the other hand Central and Eastern Europe could use more wastewater treatment plants these types of plants would drastically help the water quality in Central and Eastern Europe by removing harmful bacterias, animal wastes and pollutants and then recycling the clean water back into their system.. Soil There are many different types of soil pollution that hurt the environment ND by treating Sewage before dumping wastes would cut back on many of the current environmental issues. Spraying pesticides may be good for the crops but MIS destroying the soil and the drain off into the water system is affected by this as well. Cutting down on the usage of fossil fuels would create less solid waste and harmful gases that may seep into the soil. Eastern Europe needs to adapt to more of these possible solutions. Using low sulfur coals, Scrubbers and limestone in the remedies of air pollution would set a chain reaction in the environment the water would then become leaner along with the soil. These remedies may not fix the issue completely for Eastern Europe, but it would help them greatly. Efforts to correct Central and Eastern Europe have been left untouched since the end of the Nazi/German rule and the fall of the Great Berlin Wall on November 9th, 1989. Many of the people living in such a terrible environment still struggle every day to survive, but it is not a war against other countries it has turned into an environmental war and one that is near impossible for them to win without help. As with most all larger countries around the world Eastern and Central Europe are suffering from the same types of environmental issues but, in their case they do not have the means that we do in order to make the necessary changes that they need. Practical and low cost solutions need to be the wave of the future and used as often as possible. The problems need to be prioritize based on the highest health risk and the surrounding public will be educated and involved in its own environmental decision making. AIR- Airborne pollution is said to be one of the greatest environmental risks identified in the region. There is a large amount of sulfur dioxide found in the IR, it comes from several different places but are byproducts of several different types of older industrial facilities like the old coal burning power plants that used to be found there (ERA). The Ignited states are one of the few countries in which it is a law for vehicle owners to participate in an annual emissions test. The Czech government however has accelerated its efforts in cleaning the air pollution through it $240 million project that will assist its residents in converting homes from coal to natural gas in hopes to subsidize conversion costs (EPA). Along with this local agencies in many areas lack the equipment needed to assess and identify local problems so the Krakow Air Monitoring project. This project is under the supervision of the EPA and the Polish environmental experts are working together to identify and measure the major sources of industrial, residential and vehicle emissions testing (EPA). Along with such a huge problem facing the countries the EPA has also transferred some very low-cost techniques to help them out. Water pollution- Along with clean air there is the Krakow Water and Wastewater Improvement project, the idea here is to provide safe drinking water to city residents. Most people are drinking from contaminated drinking sources, especially those outside of the city limits. The idea here is not only to decontaminate the water before it is consumed, but to attack the problem at the source and to educate the people of the possible affects that waste dumping in insecure facilities can have on them and their families. The Krakow project as a result installed modern connation and chlorination equipment that in turn disinfected the drinking water of 400,000 residents in the area. It also focused on the improvement the forming of the Arab River Watershed Association as well as focusing on the agricultural runoff into local streams and rivers (EPA). In addition to this a team of EPA, Wisconsin, and Latvia environmental managers have also come up with a solution to protect supplies of future ground water in Disvalues, this is where the national ground water protection strategy is based. Solid and Hazardous Waste- All types Of waste needs to be dumped somewhere and the most contaminated solid waste sites are often found on military bases in Eastern Europe. They can be found on active or former military base cites, these are still dumping ties. Children in these areas are affected the most and are still being diagnosed with very high blood-lead levels, due to these case studies the EPA has provided special equipment and training to local officials to assess possible impacts of lead exposure. Due to such high levels of exposure in certain areas additional support has been provided by Romania officials to assist areas in the cleanup of contaminated soil, the Czech Council of Ministers even committed to assist the cleanup of future development cites by approving $40 million to get started, this is called Project Ecclesia. This is to the only cleanup plan in effect there is also the Solid Waste Policy Demonstration Project, this idea helps to train local communities in the proper way to carry out more effective policies of cleaning and recycling waste. Pilot programs include the construction of new sanitary landfills, the cleanup of existing landfills, curbside recycling, are probably the most important public outreach programs taking place (EPA). Technology Transfer- the EPA has also helped with the development of a geographic information system (GIS), this system helps to track different trends that occur over time. The GIS is a computer-based mapping system that over time will Store and track other environmental information that identifies pollution source and tracks it over time. This system will help the public become more informed and promote better decision making (EPA). The Radiation and Nuclear Safety Management Project is yet one more idea that is hoped to assist different storage areas of nuclear material in a quick-turnaround of radiochemistry data in case of any future leaks and potential disasters. To be able to assist such tracking a mobile radiology laboratory was created by the EPA along tit the United Nations Development Program and SAID, have provided the Ukraine with possibly one of the worlds best equipped mobile radiation monitoring laboratories.

Zinc finger nuclease technology and its potential for modelling and treating disease The WritePass Journal

Zinc finger nuclease technology and its potential for modelling and treating disease Introduction Zinc finger nuclease technology and its potential for modelling and treating disease IntroductionMechanisms of DNA double strand break repair  Ã‚   Gene edition using ZFNs gene disruption and gene correction Gene addition Therapeutic applications of ZFNsLimitations of ZFNsReferences Related Introduction Methods to introduce site specific, stable modifications in complex genomes hold great potential, not only for the study of gene function but also for biotechnological and therapeutic applications (Sollu et al., 2010).   A promising new approach is based on zinc-finger nucleases (ZFNs), artificially constructed endonucleases that are designed to make a double strand break in a pre-determined genomic target sequence. This can then be followed by the generation of desired modifications during subsequent DNA repair. ZFNs are engineered to contain a DNA binding domain, composed of zinc finger proteins, and a non-specific endonuclease domain derived from the FokI restriction enzyme (Urnov et al., 2010). The zinc finger protein region provides a ZFN with the ability to bind to a discrete base sequence. Each zinc finger domain consists of   ÃŒ ´ 30 amino acids which fold into a ÃŽ ²ÃŽ ²ÃŽ ± structure, this is stabilised by chelation of a zinc ion by the conserved Cys2-His2 residues (Durai et al., 2005). Each domain recognises and binds to approximately 3bp of DNA. Binding to longer sequences is achieved by linking several of these zinc fingers in tandem to form zinc finger proteins. As the catalytic FokI domain must dimerise to induce a double strand break (Vanamee et al., 2001), two different ZFN subunits are designed that bind the sequence of interest in the opposite orientation and with the correct spacing. The combined target sequence is sufficient in length to be statistically unique, even in complex genomes (Sollu et al., 2010) (figure 1). ZFNs have been proven to work successfully in Arabidopsis thaliana (Zhang et al., 2010), Caenorhabditis elegans, Drosophila melanogaster (Carroll et al., 2008), zebrafish (Doyon et al., 2008), rats (Mashimo et al., 2010) and human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) (Zou et al., 2009). Mechanisms of DNA double strand break repair  Ã‚   All eukaryotic cells have effective mechanisms to repair double strand breaks in DNA. The two primary repair pathways are non-homologous end joining (NHEJ) and homologous directed repair (HDR) (Jackson and Bartek, 2009). These highly conserved pathways can be exploited to generate a defined genetic outcome across a wide range of cell types (Urnov et al., 2010). In NHEJ, the two broken ends are simply ligated back together. If the double strand break is complex, creating ends that are not compatible then repair by NHEJ will be mutagenic; the repaired DNA will contain small insertions or deletions at the site of the break, resulting in gene inactivation (Durai et al., 2005). If a double stranded oligonucleotide is provided with overhangs (sticky ends) complementary to those left by the ZFNs, it will be ligated into the chromosome, this approach can be used to add tags to endogenous genes. Alternately, two simultaneous double strand breaks made on the same chromosome can lead to a deletion of the entire intervening stretch (Lee et al., 2010) (figure 2). The other major repair pathway is HDR, a form of homologous recombination that faithfully copies the genetic information from a DNA molecule of related sequence. In HDR the 5Ê ¹ ends of the double strand break are resected to generate 3Ê ¹ single stranded tails, allowing strand invasion by donor DNA, which serves as a template for DNA replication (Durai et al., 2005). In normal double strand break repairs the DNA donor is the sister-chromatid, therefore the template is identical to the damaged DNA, resulting in a perfect form of repair. In gene targeting an exogenous donor DNA template is provided (usually an episomal or linear extrachromosomal donor) in combination to the ZFNs. If the donor DNA specifies solely a single nucleotide change, such as a restriction fragment length polymorphism (RFLP) encoding a novel allele, this will result in gene correction, that subtly edits the endogenous allele (Urnov et al., 2005). HDR can also be used for the addition of genes, if the donor pro vided carries an open reading frame (ORF), a transgene or even multiple trasngenes at the position corresponding to the site of the break, the sequence will be transferred to the chromosome (Moehle et al., 2007) (figure 2). Figure 2 | Types of genome editing made possible using ZFNs. The two primary repair pathways: non-homologous end joining (NHEJ) and homologous directed repair (HDR) with the different outcomes that can result from the introduction of a site specific DNA double strand break. Adapted from (Urnov et al., 2010). Gene edition using ZFNs gene disruption and gene correction The simplest means of gene editing is gene disruption, which takes advantage of errors introduced during DNA repair to disrupt or abolish the function of a gene or genomic region. Gene knockout (KO) is an affective tool for analysing gene function and generating model animals that recapitulate genetic disorders. Using ZFN technology, Mashimo et al., 2010 created knockout rats with X-linked Server Combined Immunodeficiency (X-SCID). They injected mRNAs encoding ZFNs designed to target the rat interleukin 2 receptor gamma (II2rg) locus, where orthologous human and mouse mutations cause X-SCID, into the pronucleus of fertilised rat oocytes. They found that the offspring carried a variety of deletion/insertion mutations, most of which were expressed as frameshift or splicing errors, resulting in no or very little expression of II2rg mRNA. The ZFN modified founders faithfully transmitted their genetic changes to the next generation along with the SCID phenotype (Mashimo et al., 2010). The X-SCID rats generated in studies such as this can be valuable in vivo tools for pre-clinical testing during drug development or gene therapy as well as model systems for examining the treatment of xenotransplanted malignancies. Another approach, gene correction allows the transfer of single nucleotide changes from a DNA donor to the chromosome following a ZFN induced double strand break. Urnov et al., 2005 designed ZFNs directed against the X-linked SCID mutation hotspot in the interleukin-2 receptor-ÃŽ ³ (IL2RÃŽ ³) gene. Using the ZFNs on K562 cell lines, they found that ~20% of the population carried a modification at the endogenous loci and about 7% of the cells were homozygous for the donor specified genotype, which was accurately reflected at the mRNA and protein levels. The modified cells were found to be stable for extended periods in cell culture while transcriptionally and translationally manifesting their new genotype (Urnov et al., 2005). Gene addition Transgenesis of human cells is used in functional genomics, proteomics and protein structure-function studies, and is routinely accomplished by random integration combined with drug selection. Expression of a randomly integrated transgene can be unpredictable and tends to be unstable over time due to epigenetic effects (DeKelver et al., 2010). The precisely placed double strand break induced by ZFNs can stimulate integration of long DNA stretches into a predetermined genomic location, resulting in site-specific gene addition. Moehle et al., 2007 introduced ZFNs directed against the interleukin-2 receptor-ÃŽ ³ (IL2RÃŽ ³) gene (exon 5), in combination with a DNA donor carrying a 12bp tag and a 900bp open reading frame (ORF), flanked by locus specific homology arms into HEK293 cells. After 72 hours, ~5% of the chromatids had acquired the transgene between the ZFN recognition sites (Moehle et al., 2007). ZFNs have also been used in human EPCs and iPSC to efficiently target a drug resistance marker to a specific gene. Hockemeyer et al., 2009, used ZFNs specific for the OCT4 (POU5F1) locus and a donor constructs containing a splice acceptor (SA) followed by an enhanced green fluorescent protein (eGFP)-2A-puromycin cassette. They reported expression of two proteins, a fusion protein comprising the first 132 amino acids of human OCT4 fused to eGFP (OCT4EX1-eGFP) and puromycin N-acetyltransferase, both under the control of the endogenous OCT4 promoter, therefore generating reporter cells which can monitor the pluripotent state of human ESCs (Hockemeyer et al., 2009). Therapeutic applications of ZFNs Site specific manipulation of the genome by ZFNs has revolutionised biology and holds great promise for molecular medicine (Lombardo et al., 2007). For example a corrected allele of a disease causing gene could be curative in several monogenetic diseases. Alternatively, the knockout of a gene encoding a virus receptor could be shown to eliminate rather than merely reduce infection. ZFN mediated gene disruption is the first ZFN based approach that has been taken to clinical trails, specifically for the treatment of glioblastoma (NCT01082926) and HIV (NCT00842634 and NCT01044654). In glioblastoma phase I clinical trials, the glucocorticoid receptor gene is disrupted by ZFNs as part of a T cell based cancer immunotherapy (Urnov et al., 2010). In the HIV trials, ZFNs targeting the chemokine (C-C motif) receptor type 5 (CCR5) gene have been delivered via adenoviral vector to isolated T cells from subjects. The CCR5 protein is required for certain common types of HIV infection to enter into and infect T cells. The ZFN mediated CCR5 knockout T cells then are returned to the subject.   (Perez et al., 2008). An advantage of using ZFN technology is that it creates a fully penetrant, heritable gene knockout that will persist for the lifetime of that cell and its progeny, therefore removing the need for persistent therapeutic exposure. Limitations of ZFNs A potential limitation of the ZFN targeting approach is off-target DNA breaks induced at related sequences elsewhere in the genome, which may cause unpredictable genotoxic. To overcome this, ZFNs can be designed to with longer DNA recognition sites such as 12bp-18bp, which upon dimerisation of the FokI nuclease domain will recognise a 24bp-23bp sequence (such sites are rare even in complex genomes). This alongside bioinformatic tools such as SELEX (systematic evolution of ligands by exponential enrichment) can be used determine the specificity for a ZFN DNA binding domain and generate a rank order of potential off-target site with highest similarity (Tuerk et al., 1990).   Another challenge when designing ZFNs is the choice delivery system (DNA, RNA or viral), the ideal method has proven to be dependent on cell type. Lombardo et al., 2007 found that integrase-defective lentiviral vectors (IDLV) support functional delivery of both ZFNs and donor DNA templates to a variety of cell ty pes, including haematopoietic progenitors and embryonic stem cells (Lombardo et al., 2007). Aside from the various limitations, ZFN technology has allowed site specific genome editing to become established in human cells and a number of model organisms, opening the door to a powerful range of new experimental and therapeutic possibilities. References Carroll, D., Beumer, K. J., Morton, J. J., Bozas, A. and Trautman, J. K. (2008) Gene targeting in Drosophila and Caenorhabditis elegans with zinc-finger nucleases, Methods Mol Biol, 435, pp. 63-77. DeKelver, R. C., Choi, V. M., Moehle, E. A., Paschon, D. E., Hockemeyer, D., Meijsing, S. H., Sancak, Y., Cui, X., Steine, E. J., Miller, J. C., Tam, P., Bartsevich, V. V., Meng, X., Rupniewski, I., Gopalan, S. M., Sun, H. C., Pitz, K. J., Rock, J. M., Zhang, L., Davis, G. D., Rebar, E. J., Cheeseman, I. M., Yamamoto, K. R., Sabatini, D. M., Jaenisch, R., Gregory, P. D. and Urnov, F. D. (2010) Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome, Genome Res, 20, (8), pp. 1133-42. Doyon, Y., McCammon, J. M., Miller, J. C., Faraji, F., Ngo, C., Katibah, G. E., Amora, R., Hocking, T. D., Zhang, L., Rebar, E. J., Gregory, P. D., Urnov, F. D. and Amacher, S. L. (2008) Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases, Nat Biotechnol, 26, (6), pp. 702-8. Durai, S., Mani, M., Kandavelou, K., Wu, J., Porteus, M. H. and Chandrasegaran, S. (2005) Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells, Nucleic Acids Res, 33, (18), pp. 5978-90. Hockemeyer, D., Soldner, F., Beard, C., Gao, Q., Mitalipova, M., DeKelver, R. C., Katibah, G. E., Amora, R., Boydston, E. A., Zeitler, B., Meng, X., Miller, J. C., Zhang, L., Rebar, E. J., Gregory, P. D., Urnov, F. D. and Jaenisch, R. (2009) Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases, Nat Biotechnol, 27, (9), pp. 851-7. Jackson, S. P. and Bartek, J. (2009) The DNA-damage response in human biology and disease, Nature, 461, (7267), pp. 1071-8. Lee, H. J., Kim, E. and Kim, J. S. (2010) Targeted chromosomal deletions in human cells using zinc finger nucleases, Genome Res, 20, (1), pp. 81-9. Lombardo, A., Genovese, P., Beausejour, C. M., Colleoni, S., Lee, Y. L., Kim, K. A., Ando, D., Urnov, F. D., Galli, C., Gregory, P. D., Holmes, M. C. and Naldini, L. (2007) Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery, Nat Biotechnol, 25, (11), pp. 1298-306. Mashimo, T., Takizawa, A., Voigt, B., Yoshimi, K., Hiai, H., Kuramoto, T. and Serikawa, T. (2010) Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases, PLoS One, 5, (1), pp. e8870. Moehle, E. A., Rock, J. M., Lee, Y. L., Jouvenot, Y., DeKelver, R. C., Gregory, P. D., Urnov, F. D. and Holmes, M. C. (2007) Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases, Proc Natl Acad Sci U S A, 104, (9), pp. 3055-60. Perez, E. E., Wang, J., Miller, J. C., Jouvenot, Y., Kim, K. A., Liu, O., Wang, N., Lee, G., Bartsevich, V. V., Lee, Y. L., Guschin, D. Y., Rupniewski, I., Waite, A. J., Carpenito, C., Carroll, R. G., Orange, J. S., Urnov, F. D., Rebar, E. J., Ando, D., Gregory, P. D., Riley, J. L., Holmes, M. C. and June, C. H. (2008) Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases, Nat Biotechnol, 26, (7), pp. 808-16. Sollu, C., Pars, K., Cornu, T. I., Thibodeau-Beganny, S., Maeder, M. L., Joung, J. K., Heilbronn, R. and Cathomen, T. (2010) Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion, Nucleic Acids Res. Urnov, F. D., Miller, J. C., Lee, Y. L., Beausejour, C. M., Rock, J. M., Augustus, S., Jamieson, A. C., Porteus, M. H., Gregory, P. D. and Holmes, M. C. (2005) Highly efficient endogenous human gene correction using designed zinc-finger nucleases, Nature, 435, (7042), pp. 646-51. Urnov, F. D., Rebar, E. J., Holmes, M. C., Zhang, H. S. and Gregory, P. D. (2010) Genome editing with engineered zinc finger nucleases, Nat Rev Genet, 11, (9), pp. 636-46. Vanamee, E. S., Santagata, S. and Aggarwal, A. K. (2001) FokI requires two specific DNA sites for cleavage, J Mol Biol, 309, (1), pp. 69-78. Zhang, F., Maeder, M. L., Unger-Wallace, E., Hoshaw, J. P., Reyon, D., Christian, M., Li, X., Pierick, C. J., Dobbs, D., Peterson, T., Joung, J. K. and Voytas, D. F. 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Consumer behaviors case Essay Example | Topics and Well Written Essays - 500 words

Consumer behaviors case - Essay Example It seems that people are not ready for a change and that is the hardest part of the project. These are some of the facts that have contributed to the slow implementation of green marketing However, there are consumers who are loyal to the green products, believe in them, and know the benefits associated with green products. For this reason, companies should come up with strategies to incorporate green marketing. Companies ought to match the green products with the consumer’s traditional non-green products’ attributes, such as convenience, availability, price, quality, and performance. The green products should be available in nearby locations in such a way that the customers will not have to travel for long to look for the products. The green products should be available in shops that the non-green products used to be found. The price should be fair. That means that they green products should not be much expensive as compared to the non green products. Green products are more productive and of a higher quality than the non-green products. That information should be passed to the customers so that they can be attracted to the new products. The managers sh ould educated customers on the associated with the use of the green products and that will increase the sales of the green products. This will enable the consumer to relate with the products, as not much will have changed from their original package. The marketing strategies that the company adopts should also be right, with knowledge that different strategies work differently under different markets and competitive conditions. Managers should also understand the strategies and the reasons behind the strategies. Green marketing has not fulfilled its initial promise, but companies can take a more effective approach if they realize that a one-size-fits-all strategy does not exist. (JILL and PAUL 3) The company

IAS 17 Leases Essay Example | Topics and Well Written Essays - 1750 words

IAS 17 Leases - Essay Example This accounting standard is quite comprehensive in its nature such that it encompasses different aspects of leases in a very detailed manner. This section briefly analyzes 1) Scope of IAS 17, 2) Classification of Leases, 3) Accounting by Lessor, 4) Accounting by Lessee, 5) Disclosure Requirements for Lessor and, 6) Disclosure Requirements for Lessee. 1. Scope of IAS 17 The applicability of IAS 17 rests with all the leased assets except the following assets: †¢ Natural regenerative resources including oil, gas and other minerals †¢ Licensing agreements in respect of videos, manuscript, copyrights, brands, films, games etc. †¢ Investment property valued on fair value basis by lessee under IAS 40 †¢ Investment property considered as operating lease by the lessor under IAS40 †¢ Biological assets considered as finance lease by the lessee under IAS 41 †¢ Biological assets considered as operating lease by the lessor under IAS 41 2. Classification of Lease Lease s are generally classified into either finance lease or operating lease. The major distinguishing factor between a finance lease and an operating lease is the transfer of substantial risk and rewards even if the ownership is not transferred. It is important to note that the classification must be made before the commencement of the lease. The major criteria for the finance lease is as followed: †¢ At the expiry of the lease term, the ownership title is transferred to the lessee. At the inception of the lease the lessee has been provided the option to purchase the leased asset a price lower than the fair value of the asset, and there is likelihood that the option would probably be exercised by the lessee. Leased asset is provided to the lessee for a major part the useful life of the leased asset. The present value of the minimum lease payments (MLP) should be approximately equal to the fair value of the leased asset at the inception of the lease. The leased assets can be used by the lessee without any significant modification in the asset due to its specialized nature. 3. Accounting by the Lessor The following accounting treatment is provided under IAS 17 for the recognition of the leased assets by the lessor: There are three major recognition criteria should be used by the lessor in respect of accounting for lease. The criteria are highlighted as under: Finance lease should be recorded by the lessor in the balance as a receivable. The amount of the receivable should be approximately equal to the net investment made in the lease by the lessor. For finance lease, the income earned from the leased asset by the lessor should be presented as a constant rate of return of the outstanding amount of the lease by lessor. For the case of operating lease, those leased assets should be recognized in the balance sheet according to the nature of the leased asset. The income earned in respect of the operating lease should be recognized on straight line basis over the lea se term of the leased asset or on the basis of any other suitable and systematic criteria. 4. Accounting by the Lessee The following accounting treatment is provided under IAS 17 for the recognition of the leased assets by the lessor: In respect of the finance lease, the